Banishing, Protection & Warding off Negativity. A recognizable symbol of divine protection in many religions & cultures. Hamsa Hand is also known as Hand of Fatima, Hand of Miriam, Hand of Mother Mary or Hamesh. The Hamsa is an ancient symbol that precedes major religions. It is said that when the hand faces upward it is protecting you from evil, or negativity from others or even your own negative thoughts.